Researchers at Edith Cowan College (ECU) are investigating the results ellagic acid, an antioxidant present in some vegetables and fruit, may have on halting and doubtlessly reversing the harm brought on by fatty liver illness.
Non-alcoholic fatty liver illness (NAFLD) is the physiological manifestation of weight problems within the liver. The prevalence of NAFLD has elevated from 25.24% in 2015 to 29.38% in 2021, and this situation now accounts for 45.8% of all circumstances of chronic-liver-disease-related deaths worldwide.
There at present exists no therapy for the long-term administration of NAFLD; nevertheless, dietary interventions have been investigated for the therapy of this illness, together with a number of polyphenolic compounds corresponding to ellagic acid.
ECU researcher Dr. Lois Balmer and Ph.D. scholar Mrs. Tharani Senavirathna famous that ellagic acid, which is present in quite a lot of meals corresponding to raspberries, pomegranate, blackberries, and pecan nuts, is widely known for its antioxidant properties, but additionally displays anti-inflammatory, antifibrotic and anticancer properties.
The paper is printed within the journal Antioxidants.
“Ellagic acid stands out as a outstanding polyphenolic compound, possessing a variety of pharmacological properties that maintain promise in treating varied persistent illnesses, together with NAFLD.
“On account of its multifaceted organic results, edible crops containing ellagic acid, and its derivatives are acknowledged as priceless useful meals for enhancing human well being. Furthermore, there’s proof suggesting that ellagic acid, when mixed with different antioxidant nutraceuticals, displays a synergistic therapeutic impact, making it a possible candidate for mixture remedy.”
Mrs. Senavirathna was concerned in a beforehand undertaken pilot examine investigating the results of a number of polyphenolic compounds on NAFLD, with ellagic acid exhibiting probably the most promise in decreasing irritation.
A bigger examine is now beneath method which may even examine at which level of the sickness therapy can be ineffective to reverse harm to the liver.
Extra info:
Tharani Senavirathna et al, Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Illness and Non-Alcoholic Steatohepatitis, Antioxidants (2024). DOI: 10.3390/antiox13040485
Edith Cowan College
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Analysis says pomegranates may supply an answer to fatty liver illness (2024, Could 27)
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